Leading Progress in Ending TB
Each year on March 24, CDC joins the global community to observe World Tuberculosis (TB) Day – an important moment to unite in support, attention, and energy to end TB. Although preventable and treatable, TB remains one of the world’s deadliest infectious diseases, taking the lives of 1.6 million people annually. With nearly 11 million people becoming ill with TB in 2021, this disease continues to prove that a threat of TB anywhere is a threat everywhere.
The theme for this year’s observance, ”Yes! We Can End TB,” highlights the determination and enthusiasm of global partners as we join forces to end the global TB epidemic. CDC is on the frontlines in 25 countries with high TB prevalence. Partnering with ministries of health, CDC is sustaining efforts to diagnose, cure, and prevent this disease. On World TB Day, CDC joins our global partners in affirming our commitment to ending TB– creating a safer America and world.
Resources
An overview of the TB burden among children and adolescents and CDC’s response.
Leadership Statement
A message from CDC Director Rochelle Walensky, MD, MPH, on World TB Day.
Click here for the full message
Global TB Elimination Champions
CDC recognizes global organizations, individuals, and initiatives that have made significant contributions to ending TB. Click on the drop-down links below for more information on their unique contributions toward eliminating TB.
Placing People at the Center of our Work
CDC is on the frontlines in some of the world’s highest-burden regions, working to understand what’s driving the spread of TB, including drug-resistant TB, and how to stop it. In India, a country with one of the highest burdens of drug-resistant TB in the world, CDC developed comprehensive, person-centered interventions to improve treatment outcomes in Mumbai’s Dharavi slum where historically less than half of individuals diagnosed with drug-resistant TB complete their treatment. Efforts included support to help clients adhere to taking their medication, monitoring for adverse events, and providing services to help link those who relocated to continued care. As a result of CDC-supported interventions, 88 percent of current drug-resistant TB patients in Dharavi remain on or have completed treatment as of January 2023.
Learn more about CDC’s impact and how the use of individualized approaches ensures that those who need care receive it.
Success Years in the Making
Through the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), CDC is spearheading efforts to address the historical gaps in providing lifesaving TB Preventive Treatment (TPT) to those at increased risk of getting TB– particularly children and people living with HIV.
Each year, in Uganda, nearly 30,000 people living with HIV will develop active TB disease. But there is hope, as a recent CDC analysis of PEPFAR data shows Uganda is stopping the spread of HIV-associated TB by providing lifesaving TPT to people living with HIV. By providing TPT at both HIV and TB clinics and leveraging partnerships with the Ministry of Health, Uganda saw a dramatic increase from less than 1 percent of eligible people receiving TPT in 2016 to nearly 90 percent in 2022. Through this dynamic approach, more people are accessing lifesaving treatment and staying in care, with TPT completion rates more than tripling during the six-year period.
Learn more about these milestones in Emerging Infectious Diseases or listen below as Dr. Deus Lukoye, an epidemiologist at CDC, discusses the impact of TPT among people living with HIV in Uganda.
CDC’s Impact Around the Globe
Learn how CDC and partners are adapting services and expanding key treatment and prevention activities to end TB.
Resources
CDC’s Division of Global HIV & TB offers the following resources, which can be shared across various networks.







Friends for International Tuberculosis Relief (FIT) has provided valuable support to the Vietnam National TB Program (NTP) through TB prevention and care strategies, technical assistance, advocacy, and research for nearly a decade. In partnership with a local social enterprise, IRD VN, FIT has successfully tested and rapidly scaled up community-based case finding for TB disease and infection. By improving TB detection and notification, FIT has become a model for building the capacity of national and local TB programs, promoting best practices, and advancing innovative approaches for health equity in care and prevention.
As a community nurse for 12 years with Partners in Health at Hospital Bon Sauveur in Cange Haiti, Yoldine Talina Jean Noël understands long hours and working weekends. Caring for patients with HIV-associated TB and multidrug-resistant TB (MDR TB), Talina has championed interventions to improve and ensure TB screening among people living with HIV (PLHIV). Talinia provides person-centered holistic care to patients with TB, paying close attention to their medical and mental health needs – often going above and beyond to collaborate with social workers, community workers, and psychologists to ensure patients with TB receive the care they need. When a patient was admitted with MDR TB and severe anemia, Talina rolled up her sleeve to donate blood when there was none.
Prior to her appointment as the Assistant Commissioner of the TB/Leprosy Control Division at the Uganda Ministry of Health, Dr. Turyahabwe Stavia served as a national multidrug resistant TB (MDR TB) coordinator. During her tenure as coordinator, Dr. Stavia provided technical oversight for the establishment and implementation of quality MDR TB care and support at the national level. As Assistant Commissioner, Dr. Stavia’s leadership has been critical in the development and implementation of a national TB strategic plan – a plan that keeps the individual at the center of treatment and care. In just three years, the innovative plan has proved to be a steady guide as the Ministry of Health and implementing partners transformed the national TB program. By the end of 2021, Uganda enrolled over one million people living with HIV on TB preventive treatment, surpassing the target set at the United Nations High-Level Meeting by 346 percent. In addition, from 2017 to 2022, TB case notifications increased by 40 percent. The accolades continued in 2022, with the World Health Organization declaring Uganda as one of the first countries with a high TB burden to achieve the milestone of the end TB strategy – reducing TB death by more than 35 percent when compared to 2015 levels.
In 2022, Ukraine Public Health Center, in partnership with CDC-Ukraine, undertook an innovative project to evaluate the impact of the TB Preventive Treatment (TPT) program among people living with HIV (PLHIV) in high multidrug-resistant TB (MDR TB) settings. Through continuous engagement with CDC in Atlanta, the team in Ukraine was able to conduct the evaluation despite being displaced and forced to flee the country due to the Russian invasion. However, some team members did remain in the capital city of Kyiv, where they continued to support the project, often dealing with electricity outages or bombing alerts. Not once did they say this work needed to stop because of ongoing conflict. This evaluation completed by the PROTECT Team provides the first large-scale data from a nationwide public health surveillance system showing isoniazid (INH) TPT is effective in decreasing TB incidence, even in a high MDR TB setting. The effect of INH TPT was independent of antiretroviral therapy and viral suppression, and importantly, it did not increase MDR TB rates among those who developed TB – providing significant implications both for TPT scale-up as well as for MDR TB prevention. As MDR TB and HIV co-infections continue to be a pressing public health problem, data supporting INH TPT effectiveness in these settings is invaluable to support TPT scale-up, not only in Ukraine but for PLHIV in other high MDR TB settings.
As CDC-Uganda’s sole TB public health specialist, Dr. Deus Lukoye, tirelessly works to stop TB among people living with HIV. Through his unique approach, founded on public health diplomacy, diverse stakeholder engagement, data-driven decision-making, and strategic science, Dr. Lukoye has been relentless in expanding CDC’s efforts to end TB in Uganda. His impact is featured in a first-authored article on the huge scale-up of TB preventive therapy (TPT) in Uganda in Emerging Infectious Diseases. This study demonstrated that TPT coverage among PLHIV increased from less than 1 percent in October 2016 to 89 percent in March 2022.
In South Africa, Katlego Motlhaoleng serves as a TB/HIV public health specialist providing technical guidance to the South African National Department of Health and PEPFAR District Support Partners on the development, implementation, and monitoring of TB/HIV program activities designed to improve patient health outcomes. Her reach in ending TB extends to the policy level, where she contributed to the development and approval of the Targeted Universal TB Testing guidelines and the revised TPT guidelines. Katelgo’s efforts have improved PEPFAR-supported programs through a 36 percent year-over-year increase in TB case finding, achieving the 1st and 2nd UNAIDS goals in TB/HIV programming in FY22- Q4, and increasing the year-over-year TPT completion by 4 percent.

