History of vigorous leisure-time physical activity and early onset amyotrophic lateral sclerosis (ALS), data from the national ALS registry: 2010–2018

For Public Health

Key points

Characterized the association between vigorous physical activity (VPA) during adolescence and early adulthood and receiving an amyotrophic lateral sclerosis diagnosis. Study found a positive association between VPA before age 35 and receiving an ALS diagnosis.
Screenshot of the first two pages of the paper

Affiliates

Jaime Raymond [1], Paul Mehta [1], Ted Larson [1], Pam Factor-Litvak [2], Bryn Davis [1], and Kevin Horton [1]

  1. Agency for Toxic Substances and Disease Registry/Centers for Disease Control and Prevention
  2. Mailman School of Public Health, Columbia University

Journal

Amyotrophic lateral sclerosis and frontotemporal degeneration

Summary

This study sought to further characterize the association between vigorous physical activity (VPA) during adolescence and early adulthood and receiving an amyotrophic lateral sclerosis (ALS) diagnosis. Linear regression estimates suggest a positive association between VPA before age 35 and receiving an ALS diagnosis.

Link to Paper

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Content Source
Agency for Toxic Substances and Disease Registry
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Published: November 12, 2024
Updated: November 11, 2024

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Reviewed: September 10, 2026

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