A brief report on juvenile amyotrophic lateral sclerosis cases in the United States National ALS Registry: 2010–2018

For Public Health

Key points

Demographic characteristics of juvenile ALS (jALS), designated as presenting ALS symptoms before age 25, in the United States between 2010 and 2018. Forty-four cases of were identified in National ALS Registry data, of which the majority were non-white and male. More research is needed to better understand risk factors contributing to jALS, which could lead to earlier diagnosis and therapeutic interventions.
Screenshot of the first two pages of Raymond 2023 - Juvenile paper

Affiliates

Jaime Raymond [1], Jasmine Berry [1], Edward J. Kasarskis [2], Theodore Larson [1], D. Kevin Horton [1] and Paul Mehta [1]

  1. Agency for Toxic Substances and Disease Registry/Centers for Disease Control and Prevention, Atlanta, GA, USA
  2. Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA

Journal

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Summary

This paper describes the demographic characteristics of Juvenile ALS (jALS), designated as presenting ALS symptoms before age 25, in the United States between 2010 and 2018. Forty-four cases of were identified in National ALS Registry data, of which the majority were non-white and male. More research is needed to better understand risk factors contributing to jALS, which could lead to earlier diagnosis and therapeutic interventions.

Link to Paper

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Content Source
Agency for Toxic Substances and Disease Registry
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Published: November 12, 2024
Updated: November 11, 2024

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Reviewed: September 10, 2026

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