Table 14B. Primary and Secondary Syphilis Among Women — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2017–2021

Table 14B. Primary and Secondary Syphilis Among Women — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2017–2021
State/Territory Cases Rates per 100,000 Population
2017 2018 2019 2020 2021 2017 2018 2019 2020 2021
Alabama 70 88 126 116 193 2.8 3.5 5.0 4.5 7.4
Alaska 1 4 50 65 79 0.3 1.1 14.3 18.6 22.7
Arizona 158 177 240 314 482 4.5 4.9 6.6 8.8 13.2
Arkansas 64 68 121 206 426 4.2 4.4 7.9 13.5 27.8
California 902 1,255 1,494 1,520 1,962 4.5 6.3 7.5 7.7 10.0
Colorado 18 25 62 99 198 0.6 0.9 2.2 3.5 6.9
Connecticut 13 5 20 30 74 0.7 0.3 1.1 1.6 4.0
Delaware 6 7 17 14 28 1.2 1.4 3.4 2.8 5.4
District of Columbia 7 12 21 23 17 1.9 3.3 5.7 6.4 4.8
Florida 321 356 460 520 725 3.0 3.3 4.2 4.8 6.5
Georgia 139 184 195 257 334 2.6 3.4 3.6 4.7 6.0
Hawaii 6 7 23 47 82 0.8 1.0 3.2 6.5 11.4
Idaho 15 5 9 21 20 1.8 0.6 1.0 2.3 2.1
Illinois 85 120 161 215 306 1.3 1.9 2.5 3.3 4.8
Indiana 27 26 54 88 156 0.8 0.8 1.6 2.6 4.6
Iowa 9 11 35 24 73 0.6 0.7 2.2 1.5 4.6
Kansas 16 24 33 26 63 1.1 1.6 2.3 1.8 4.3
Kentucky 41 70 101 112 135 1.8 3.1 4.5 4.9 5.9
Louisiana 186 166 163 177 273 7.8 7.0 6.8 7.5 11.6
Maine 9 7 6 1 9 1.3 1.0 0.9 0.1 1.3
Maryland 47 81 121 140 NR 1.5 2.6 3.9 4.4
Massachusetts 26 41 59 62 65 0.7 1.2 1.7 1.7 1.8
Michigan 34 69 95 113 207 0.7 1.4 1.9 2.2 4.1
Minnesota 38 44 70 85 144 1.4 1.6 2.5 3.0 5.1
Mississippi 88 152 258 296 343 5.7 9.9 16.8 19.5 22.6
Missouri 93 161 178 253 452 3.0 5.2 5.7 8.1 14.5
Montana 9 10 20 8 44 1.7 1.9 3.8 1.5 8.1
Nebraska 7 14 22 18 55 0.7 1.4 2.3 1.8 5.6
Nevada 75 119 159 150 199 5.0 7.9 10.4 9.7 12.8
New Hampshire 4 3 4 6 8 0.6 0.4 0.6 0.9 1.1
New Jersey 34 58 73 116 156 0.7 1.3 1.6 2.5 3.3
New Mexico 19 46 135 141 248 1.8 4.3 12.7 13.3 23.3
New York 121 171 231 268 406 1.2 1.7 2.3 2.6 4.0
North Carolina 127 160 186 207 360 2.4 3.0 3.5 3.9 6.7
North Dakota 5 10 14 11 6 1.4 2.7 3.8 2.9 1.6
Ohio 112 92 114 202 392 1.9 1.5 1.9 3.4 6.6
Oklahoma 67 144 244 338 417 3.4 7.2 12.2 17.0 20.8
Oregon 52 92 105 152 287 2.5 4.4 4.9 7.2 13.5
Pennsylvania 76 99 133 134 192 1.2 1.5 2.0 2.0 2.9
Rhode Island 7 12 7 11 26 1.3 2.2 1.3 2.0 4.7
South Carolina 56 67 104 197 230 2.2 2.6 3.9 7.5 8.6
South Dakota 4 11 15 27 185 0.9 2.5 3.4 6.2 42.0
Tennessee 47 67 105 141 255 1.4 1.9 3.0 4.0 7.2
Texas 313 424 416 583 1,045 2.2 2.9 2.9 4.0 7.1
Utah 4 10 12 12 26 0.3 0.6 0.8 0.7 1.6
Vermont 1 2 1 0 1 0.3 0.6 0.3 0.0 0.3
Virginia 60 77 66 78 94 1.4 1.8 1.5 1.8 2.2
Washington 70 100 117 159 338 1.9 2.7 3.1 4.2 8.8
West Virginia 21 19 20 45 93 2.3 2.1 2.2 5.0 10.4
Wisconsin 12 18 17 72 214 0.4 0.6 0.6 2.4 7.3
Wyoming 0 5 1 1 5 0.0 1.8 0.4 0.4 1.8
US TOTAL 3,722 4,995 6,493 7,901 12,265 2.3 3.0 3.9 4.7 7.3
   Northeast 291 398 534 628 937 1.0 1.4 1.9 2.1 3.2
   Midwest 442 600 808 1,134 2,253 1.3 1.7 2.3 3.3 6.5
   South 1,660 2,142 2,724 3,450 5,105 2.6 3.4 4.3 5.4 7.9
   West 1,329 1,855 2,427 2,689 3,970 3.4 4.7 6.2 6.9 10.1
American Samoa NR 0 0 0 0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands NR 0 0 0 0 0.0 0.0 0.0 0.0
Guam 2 0 0 1 0 2.5 0.0 0.0 1.2 0.0
Puerto Rico 66 52 52 56 62 3.8 3.0 3.1 3.2 3.6
Virgin Islands 0 NR NR 1 1 0.0 1.8 1.8
TERRITORIES TOTAL 68 52 52 58 63 3.6 2.8 2.9 3.0 3.3
TOTAL 3,790 5,047 6,545 7,959 12,328 2.3 3.0 3.9 4.7 7.3
NR = No report.

NOTE: Cases reported with unknown sex are not included in this table. See Technical Notes for more information on interpreting case counts and rates in US territories. The COVID-19 pandemic has introduced uncertainty and difficulty in interpreting STD data collected during 2020 and 2021. See Impact of COVID-19 on STDs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STD case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.

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