TY  - JOUR
AU  - Lutski, Miri
AU  - Weinstein, Galit
AU  - Tanne, David
AU  - Goldbourt, Uri
PY  - 2020
TI  - Overweight, Obesity, and Late-Life Sarcopenia Among Men With Cardiovascular Disease, Israel
T2  - Preventing Chronic Disease
JO  - Prev Chronic Dis
SP  - E164
VL  - 17
CY  - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
N2  - INTRODUCTION  Little is known about the association between obesity and sarcopenia - age-related loss of muscle mass and function - among patients with cardiovascular disease. We investigated the association between overweight, obesity, and sarcopenia among community-dwelling men in Israel with cardiovascular disease. METHODS  A subset of 337 men (mean age at baseline 56.7 [SD, 6.5]) who previously (1990-1997) participated in the Bezafibrate Infarction Prevention trial underwent a neurovascular evaluation as part of the Bezafibrate Infarction Prevention Neurocognitive Study 15.0 (SD, 3.0) years after baseline and a sarcopenia evaluation 19.9 (SD, 1.0) years after baseline. We applied a multinomial logistic model to estimate odds ratios and 95% CIs for 3 categories of sarcopenia: no evidence of sarcopenia (ie, robust), probable sarcopenia, and sarcopenia. RESULTS  We found sarcopenia among 54.3% of participants with obesity (body mass index [BMI, in kg/m2] >=30.0), 37.0% of participants who were overweight (25.0 <= BMI <=29.9), and 24.8% of participants with normal weight (BMI 18.5 to 24.9). In a comparison of BMI >=25.0 and BMI <25.0, adjusting for covariates, the odds ratio of having probable sarcopenia was 3.27 (95% CI, 1.68-6.36) and having sarcopenia was 5.31 (95% CI, 2.50-11.27). CONCLUSION  We found a positive association between obesity and late-life sarcopenia and suggest that obesity might be an important modifiable risk factor related to sarcopenia among men with cardiovascular disease.
SN  - 1545-1151
UR  - https://doi.org/10.5888/pcd17.200167
DO  - 10.5888/pcd17.200167
ER  - 
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