TY  - JOUR
AU  - Pacheco, Lorena Sonia
AU  - Blanco, Estela
AU  - Burrows, Raquel
AU  - Reyes, Marcela
AU  - Lozoff, Betsy
AU  - Gahagan, Sheila
PY  - 2017
TI  - Early Onset Obesity and Risk of Metabolic Syndrome Among Chilean Adolescents
T2  - Preventing Chronic Disease
JO  - Prev Chronic Dis
SP  - E93
VL  - 14
CY  - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
N2  - INTRODUCTION  Obesity and metabolic syndrome (MetS) indicators have increased globally among the pediatric population. MetS indicators in the young elevate their risk of cardiovascular disease and metabolic disorders later in life. This study examined early onset obesity as a risk factor for MetS risk in adolescence. METHODS  A cohort of Chilean participants (N = 673) followed from infancy was assessed at age 5 years and in adolescence (mean age, 16.8 y). Adiposity was measured at both time points; blood pressure and fasting blood samples were assessed in adolescence only. Early onset obesity was defined as a World Health Organization z score of 2 standard deviations (SDs) or more for body mass index (BMI) at age 5 years. We used linear regression to examine the association between early onset obesity and adolescent MetS risk z score, adjusting for covariates. RESULTS  Eighteen percent of participants had early onset obesity, and 50% of these remained obese in adolescence. Mean MetS risk z score in adolescence was significantly higher among those with early onset obesity than among those without (1.0; SD, 0.8 vs 0.2; SD, 0.8 [P < .001]). In the multivariable model, early onset obesity independently contributed to a higher MetS risk score in adolescence (beta = 0.27, P < .001), controlling for obesity status at adolescence and sex, and explained 39% of the variance in MetS risk. CONCLUSION  Early onset obesity as young as age 5 years relates to higher MetS risk.
SN  - 1545-1151
UR  - https://doi.org/10.5888/pcd14.170132
DO  - 10.5888/pcd14.170132
ER  - 
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