Screening Flowchart: Figure 2

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Tuberculosis Screening for Applicants in High Tuberculosis Burden Countries

1. If “Tuberculosis Screening for Applicants 2 – 14 Years of Age in High TB burden countries*”, then
   1. If “For all applicants 2 through 14 years of age in high tuberculosis burden countries”, then
      1. “Medical history”
      2. “Physical examination”
      3. “IGRA”
   2. If “For those with a positive IGRA or signs or symptoms of tuberculosis or known HIV infection”, then
      1. “Chest x-ray”
   3. If “For those with a chest x-ray suggestive of tuberculosis, or signs or symptoms of tuberculosis, or known HIV infection”, then
      1. “Three sputum smears and three cultures for M. tuberculosis”
   4. If “For those with positive cultures”, then
      1. “Drug susceptibility testing”

* Tuberculosis screening for applicants 2 through 14 years of age in countries with a WHO-estimated tuberculosis disease incidence rate ≥20 cases per 100,000 population.

2. If “Tuberculosis screening for applicants 15 years of age or older in high TB burden countries*”, then
   1. If “For all applicants ≥15 years of age in high tuberculosis burden countries”, then
      1. “Medical history”
      2. “Physical examination”
      3. “Chest x-ray”
   2. If “For those with chest x-ray suggestive of tuberculosis, or signs or symptoms of tuberculosis, or known HIV infection”, then
      1. “Three sputum smears and three cultures for M. tuberculosis”
   3. If “For those with positive cultures”, then
      1. “Drug susceptibility testing”

* Tuberculosis screening for applicants ≥15 years of age in countries with a WHO-estimated tuberculosis disease incidence rate ≥20 cases per 100,000 population.